GATAD1 is involved in sphingosylphosphorylcholine-attenuated myocardial ischemia-reperfusion injury by modulating myocardial fatty acid oxidation and glucose oxidation

Modulating the equilibrium between glucose metabolism and fatty acid metabolism represents highly promising novel strategies for therapy of myocardial ischemia/reperfusion (I/R) injury. Sphingosylphosphorylcholine (SPC), an intermediate metabolite of sphingolipids, has shown cardioprotective roles d...

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Veröffentlicht in:Free radical biology & medicine 2025-02, Vol.227, p.166-178
Hauptverfasser: Cai, Yuqing, Yu, Yifan, Zhang, Tianliang, Qian, Baoshuo, Wang, Benlong, Yan, Wenxiu, Zhao, Jing
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Sprache:eng
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