Global trends in the application of droplet digital PCR technology in the field of infectious disease pathogen diagnosis: A bibliometric analysis from 2012 to 2023

Global trends in the application of droplet digital PCR technology in the field of infectious disease pathogen diagnosis: A bibliometric analysis from 2012 to 2023

This study discusses the development trends and current applications of digital droplet PCR technology in pathogen diagnostics. A bibliometric analysis was conducted by retrieving droplet digital pcr related articles published between January 1,2012 to December31, 2023, from the Web of Science Core...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 2025-03, Vol.111 (3), p.116623, Article 116623
Hauptverfasser: Yang, Xiaojie, Yu, Fengting, Yan, Chang, Li, Mengying, Liang, Xuelei, Lao, Xiaojie, Sun, Rui, Lv, Wenhao, Zhang, Hanxi, Zhang, Fujie
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Bibliometric analysis
Droplet Digital PCR
Pathogen
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container_end_page
container_issue 3
container_start_page 116623
container_title Diagnostic microbiology and infectious disease
container_volume 111
creator Yang, Xiaojie
Yu, Fengting
Yan, Chang
Li, Mengying
Liang, Xuelei
Lao, Xiaojie
Sun, Rui
Lv, Wenhao
Zhang, Hanxi
Zhang, Fujie
description This study discusses the development trends and current applications of digital droplet PCR technology in pathogen diagnostics. A bibliometric analysis was conducted by retrieving droplet digital pcr related articles published between January 1,2012 to December31, 2023, from the Web of Science Core Collection. A total of 3,513 authors from 66 countries published 508 research papers across 203 academic institutions. The keyword clustering network shows that the main advantages of ddPCR are absolute quantification, high sensitivity, and high tolerance to PCR inhibitors. The keyword timeline shows that current research hotspots include continuous pathogen nucleic acid monitoring, trace sample detection, and resistance mutation identification. The application of ddPCR in pathogen diagnosis is expanding, offering key advantages in absolute quantification, high sensitivity, and inhibitor tolerance, meeting emerging needs in nucleic acid monitoring and resistance detection.
doi_str_mv 10.1016/j.diagmicrobio.2024.116623
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subjects Bibliometric analysis
Droplet Digital PCR
Pathogen
Vosviewer
title Global trends in the application of droplet digital PCR technology in the field of infectious disease pathogen diagnosis: A bibliometric analysis from 2012 to 2023
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