Single-cell analysis of human peripheral blood reveals high immune response activity in successful ageing individuals

Beneficial remodeling of the immune system in successful ageing individuals (centenarians and supercentenarians) is critical for healthy ageing. However, mechanisms for dynamic regulation of immunity during ageing remain unclear. We use single-cell RNA sequencing (scRNA-seq) as an analytical strateg...

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Veröffentlicht in:	Mechanisms of ageing and development 2025-02, Vol.223, p.112011, Article 112011
Hauptverfasser:	Wang, Yu, Zhang, Yuxing, Gong, Ge, Liu, Quanzhong, Li, Liangyu, Zhang, Mingjiong, Shen, Shuping, Wang, Ran, Wu, Jianqing, Xu, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing CD8+ T cells Centenarian Immune Single-cell transcriptome
Online-Zugang:	Volltext
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