Cardiovascular effects of early maternal separation and escitalopram treatment in rats with depressive-like behaviour

Depression and cardiovascular diseases are two of the world's major health problems. Escitalopram (ESC) is widely used because of its safety in relation to other drugs in that class; however, it can affect the cardiovascular system. The present study evaluated the cardiovascular parameters of d...

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Veröffentlicht in:	Autonomic neuroscience 2024-12, Vol.256, p.103223, Article 103223
Hauptverfasser:	Veríssimo, Luiz Fernando, Alves, Fernando Henrique Ferrari, Estrada, Viviane Batista, da Costa Marques, Leonardo Andre, Andrade, Karoliny Coelho, Bonancea, Amanda Monteiro, Okano, Natália Tavares, Corrêa, Fernando Morgan de Aguiar, Pelosi, Gislaine Garcia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents, Second-Generation - pharmacology Baroreflex - drug effects Baroreflex - physiology Blood Pressure - drug effects Blood Pressure - physiology Cardiovascular safety Citalopram - pharmacology Depression Depression - drug therapy Depression - physiopathology Depressive-like behaviour Disease Models, Animal Escitalopram - pharmacology Female Heart Rate - drug effects Male Maternal Deprivation Phenylephrine - pharmacology Rats Rats, Wistar Selective serotonin reuptake inhibitor
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