Bifunctional nanomaterial enabled high-specific isolation of urinary exosomes for cervical cancer metabolomics analysis and biomarker discovery

Cervical cancer (CC) remains a critical public health issue, highlighting the importance of early detection. However, current methods such as cytological and HPV testing face challenges of invasiveness and low patient compliance. Exosomes, emerging as crucial in cancer diagnosis, offer promise due t...

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Veröffentlicht in:	Talanta (Oxford) 2025-04, Vol.285, p.127280, Article 127280
Hauptverfasser:	Cao, Yiqing, Qin, Yulin, Cheng, Qunxian, Zhong, Jialiang, Han, Bing, Li, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers, Nucleotide - chemistry Biomarkers, Tumor - urine Cervical cancer Exosome Exosomes - chemistry Female Humans Isolation Metabolomics - methods Nanomaterial Nanostructures - chemistry Tetraspanin 30 - metabolism Uterine Cervical Neoplasms - diagnosis Uterine Cervical Neoplasms - urine
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