Validation of the Lung Immune Prognostic Index in patients with untreated advanced non-small cell lung cancer: Post hoc analysis of the IMpower 130, 131 and 150 trials

•LIPI is prognostic for PFS and OS in prospective trials in aNSCLC.•LIPI is prognostic across all treatments regimens.•LIPI poor patients derived no benefit from chemo-immunotherapy combinations compared to chemotherapy alone.•LIPI combined to PD-L1 may improve the upfront treatment selection. LIPI...

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Veröffentlicht in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2025-01, Vol.199, p.108039, Article 108039
Hauptverfasser: Auclin, Edouard, Roulleaux Dugage, Matthieu, Gorria, Teresa, Vauchier, Charles, Thibault, Constance, Laguna, Juan Carlos, Lupinacci, Lorena, Crous, Carme, Naigeon, Marie, Oudard, Stéphane, Besse, Benjamin, Mezquita, Laura
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Sprache:eng
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