New insight into the molecular etiopathogenesis of konzo: Cyanate could be a plausible neurotoxin contributing to konzo, contrary to thiocyanate

Chronic cassava-derived cyanide poisoning is associated with the appearance of konzo, a tropical spastic paraparesis due to selective upper motor neuron damage. Whether the disease is caused by a direct action of cyanide or its metabolites is still an open question. This preliminary study assessed t...

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Veröffentlicht in:Neurotoxicology (Park Forest South) 2024-12, Vol.105, p.323-333
Hauptverfasser: Baguma, Marius, Kessels, Sofie, Bito, Virginie, Brône, Bert, Triller, Antoine, Maynard, Stéphanie, Legendre, Pascal, Rigo, Jean-Michel, Le Corronc, Hervé, Chabwine, Joelle Nsimire
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Sprache:eng
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