Genome-wide investigation of VNTR motif polymorphisms in 8,222 genomes: Implications for biological regulation and human traits

Variable number tandem repeat (VNTR) is a pervasive and highly mutable genetic feature that varies in both length and repeat sequence. Despite the well-studied copy-number variants, the functional impacts of repeat motif polymorphisms remain unknown. Here, we present the largest genome-wide VNTR pol...

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Veröffentlicht in:	Cell genomics 2024-12, Vol.4 (12), p.100699, Article 100699
Hauptverfasser:	Zhang, Sijia, Song, Qiao, Zhang, Peng, Wang, Xiaona, Guo, Rong, Li, Yanyan, Liu, Shuai, Yan, Xiaoyu, Zhang, Jingjing, Niu, Yiwei, Shi, Yirong, Song, Tingrui, Xu, Tao, He, Shunmin
Format:	Artikel
Sprache:	eng
Schlagworte:	gene regulation Genome, Human Genome-Wide Association Study Humans Minisatellite Repeats - genetics motif polymorphism Polymorphism, Genetic PU.1 tandem repeat VNTR whole-genome sequencing
Online-Zugang:	Volltext
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