Evaluating and reporting LET and RBE-weighted dose in proton therapy for glioma – The Dutch approach

•The Dutch Proton Therapy network created a guideline on glioma LET and RBE evaluation.•For LET, dose averaged LET is reported for protons calculated in water.•The McNamara RBE model is used with an α/β value of 2 Gy.•The harmonization can uniform clinical and scientific exchanges and comparisons.•T...

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Veröffentlicht in:	Radiotherapy and oncology 2025-01, Vol.202, p.110653, Article 110653
Hauptverfasser:	Wagenaar, Dirk, Habraken, Steven J.M., Rinaldi, Ilaria, Eekers, Daniëlle B.P., Kramer, Miranda, Jaspers, Jaap P.M., van Gent, Dik, Barazzuol, Lara, Klaver, Yvonne L.B., Zindler, Jaap, Coremans, Ida, Compter, Inge, Scandurra, Daniel, van der Weide, Hiska L., Both, Stefan, Hoogeman, Mischa, Unipan, Mirko, Méndez Romero, Alejandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Glioma Linear Energy Transfer (LET) Proton therapy Relative Biological Effectiveness (RBE)
Online-Zugang:	Volltext
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