Effects of metformin on binge‐like ethanol drinking and adenosine monophosphate kinase signaling in inbred high drinking in the dark line 1 mice

Background Adenosine monophosphate‐activated protein kinase (AMPK) signaling plays a vital role in regulating cellular metabolism and energy throughout the body. Ethanol and cocaine both reduce AMPK activity in addiction‐related brain regions. Though AMPK activation has been found to reduce cocaine...

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Veröffentlicht in:Alcohol, clinical & experimental research clinical & experimental research, 2024-12, Vol.48 (12), p.2269-2280
Hauptverfasser: Grigsby, Kolter, Palacios, Jonathan, Chan, Amy E., Spencer, Sade M., Ozburn, Angela R.
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Sprache:eng
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