Tranexamic Acid Within 4.5 Hours of Intracerebral Hemorrhage With the CTA Spot Sign: Systematic Review and Individual Patient Meta-analysis

The antifibrinolytic agent tranexamic acid has been tested in intracerebral hemorrhage trials with overall neutral results. Ongoing contrast extravasation on CT angiography (spot sign) can identify individuals with ongoing bleeding who may benefit from anti-fibrinolytic therapy. We aimed to investig...

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Veröffentlicht in:	Neurology 2024-12, Vol.103 (12), p.e210104
Hauptverfasser:	Yassi, Nawaf, Yogendrakumar, Vignan, Churilov, Leonid, Meretoja, Atte, Wu, Teddy, Campbell, Bruce C V, Strbian, Daniel, Jeng, Jiann-Shing, Woodhouse, Lisa J, Ovesen, Christian, Law, Zhe Kang, Gu, Hong-Qiu, Nie, Ximing, Liu, Jingyi, Ma, Henry H, Zhao, Henry, Bath, Philip M, Liu, Liping, Sprigg, Nikola, Donnan, Geoffrey Alan, Davis, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifibrinolytic Agents - administration & dosage Antifibrinolytic Agents - therapeutic use Cerebral Hemorrhage - diagnostic imaging Cerebral Hemorrhage - drug therapy Computed Tomography Angiography Hematoma - diagnostic imaging Hematoma - drug therapy Humans Tranexamic Acid - administration & dosage Tranexamic Acid - therapeutic use
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