Deciphering the potential of Cymbopogon citratus (DC.) Stapf as an anti-obesity agent: phytochemical profiling, in vivo evaluations and molecular docking studies

Based on its anti-inflammatory and antioxidant properties, (DC) Stapf is commonly used in traditional and modern medicine to cure different diseases. The present study investigates the potential of organic extract as an anti-obesity drug in a HCHFD (high-carbohydrate, high-fat diet) model for obese...

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Veröffentlicht in:	Food & function 2024-12, Vol.15 (24), p.12146-12168
Hauptverfasser:	Aly, Omnia, Mekky, Reham Hassan, Pereira, Florbela, Diab, Yasser M, Tammam, Mohamed A, El-Demerdash, Amr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Animals Anti-Obesity Agents - chemistry Anti-Obesity Agents - pharmacology Biocompatibility Blood Glucose - drug effects Blood Glucose - metabolism Carbohydrates Cymbopogon - chemistry Cymbopogon citratus Data acquisition Diet, High-Fat - adverse effects Enzyme-linked immunosorbent assay Evaluation Flavones Gene expression Glycosylation High carbohydrate diet High fat diet Hydrogen bonds Hydroxycinnamic acid In vivo methods and tests Lipids Liquid chromatography Male Metabolites Molecular docking Molecular Docking Simulation Molecular structure Obesity Obesity - drug therapy Obesity - metabolism Pharmacokinetics Phenols Phytochemicals - chemistry Phytochemicals - pharmacology Plant extracts Plant Extracts - chemistry Plant Extracts - pharmacology Proteins Rats Real time Secondary metabolites Toxicity
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