Crosstalk in Skin: Loss of Desmoglein 1 in Keratinocytes Inhibits BRAFV600E-Induced Cellular Senescence in Human Melanocytes

Melanoma arises from transformation of melanocytes in the basal layer of epidermis where they are surrounded by keratinocytes, with which they interact through cell contact and paracrine communication. Although research focuses on how the accumulation of oncogene and tumor suppressor gene mutations...

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Veröffentlicht in:	Journal of investigative dermatology 2024-11
Hauptverfasser:	Tong, Xin, Burks, Hope E., Ren, Ziyou, Koetsier, Jennifer L., Roth-Carter, Quinn R., Green, Kathleen J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Desmoglein1 Keratinocyte Melanocyte Netrin-4 Senescence
Online-Zugang:	Volltext
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