MiR-433 inhibits cell invasion of glioblastoma via direct targeting TRPM8 based on bioinformatic analysis and experimental validation

•miRNA’s pivotal role in glioblastoma invasion.•WGCNA analysis of miRNA data from GEO.•miR-433 targeting TRPM8 validated.•Inhibition of glioblastoma invasion by miR-433/TRPM8 axis. Understanding the essential role of miRNA in regulating cell invasion in glioblastoma opens up new avenues for targeted...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Gene 2025-02, Vol.936, p.149121, Article 149121
Hauptverfasser:	Zeng, Jianping, Tong, Shoufang, Liu, Jing, Liu, Shuai, Mungur, Rajneesh, Chen, Shangshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Brain Neoplasms - genetics Brain Neoplasms - metabolism Brain Neoplasms - pathology Cell Line, Tumor Cell Movement - genetics Computational Biology - methods Gene Expression Regulation, Neoplastic Gene Regulatory Networks Glioblastoma Glioblastoma - genetics Glioblastoma - metabolism Glioblastoma - pathology Humans Invasion MicroRNAs - genetics MicroRNAs - metabolism miR-433 Neoplasm Invasiveness TRPM Cation Channels - genetics TRPM Cation Channels - metabolism TRPM8
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!