Suffruticosol B from Paeonia lactiflora Ameliorates Alzheimer's Disease Pathology by Inhibiting MAO-B Activity

Monoamine oxidase B (MAO-B) has emerged as a therapeutic target for Alzheimer's disease (AD) due to its involvement in the synthesis of γ-aminobutyric acid (GABA) in reactive astrocytes, which inhibits neuronal activity. Suffruticosol B (Suf-B), isolated from Paeonia lactiflora, is one of the r...

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Veröffentlicht in:	Phytotherapy research 2024-11
Hauptverfasser:	Heo, Jae-Jun, Han, Young-Eun, Kim, Min Soo, Cheong, Eunji, Choi, Chun Whan, Oh, Soo-Jin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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