Development of a multiplexing method for the quantification of “high-risk” host cell lipases in biotherapeutics by Luminex

Clearance of residual Host Cell Proteins (HCPs) is critical for the manufacturing processes of biotherapeutics. HCPs have the potential to impact product efficacy and quality, posing a risk to patient safety. It is therefore essential to be able to both identify and quantitate HCPs throughout drug d...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Analytica chimica acta 2024-12, Vol.1332, p.343349, Article 343349
Hauptverfasser:	Osko, Jeremy D., Rivera, Shannon, Wang, Fengqiang, Niedringhaus, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Products - analysis Biological Products - chemistry CHO Cells Cricetulus Enzyme-Linked Immunosorbent Assay - methods Humans Lipase - analysis Lipase - metabolism Lipoprotein Lipase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!