Noise-aware dynamic image denoising and positron range correction for Rubidium-82 cardiac PET imaging via self-supervision

Rubidium-82 (82Rb) is a radioactive isotope widely used for cardiac PET imaging. Despite numerous benefits of 82Rb, there are several factors that limits its image quality and quantitative accuracy. First, the short half-life of 82Rb results in noisy dynamic frames. Low signal-to-noise ratio would r...

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Veröffentlicht in:	Medical image analysis 2025-02, Vol.100, p.103391, Article 103391
Hauptverfasser:	Xie, Huidong, Guo, Liang, Velo, Alexandre, Liu, Zhao, Liu, Qiong, Guo, Xueqi, Zhou, Bo, Chen, Xiongchao, Tsai, Yu-Jung, Miao, Tianshun, Xia, Menghua, Liu, Yi-Hwa, Armstrong, Ian S., Wang, Ge, Carson, Richard E., Sinusas, Albert J., Liu, Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Deep learning Heart - diagnostic imaging Humans Image Processing, Computer-Assisted - methods Medical image denoising Positron range correction Positron-Emission Tomography - methods Rubidium Radioisotopes Rubidium-82 cardiac PET imaging Self-supervised learning Signal-To-Noise Ratio
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