Potential key pathophysiological participant and treatment target in autism spectrum disorder: Microglia

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by social and communication deficits, as well as restricted or repetitive behaviors or interests. Although the etiology of ASD remains unclear, there is abundant evidence suggesting that microglial dysfunction is...

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Veröffentlicht in:	Molecular and cellular neuroscience 2024-12, Vol.131, p.103980, Article 103980
Hauptverfasser:	Tan, Zehua, Xia, Ruixin, Zhao, Xin, Yang, Zile, Liu, Haiying, Wang, Wenting
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autism spectrum disorder Autism Spectrum Disorder - genetics Autism Spectrum Disorder - metabolism Autism Spectrum Disorder - physiopathology Brain - metabolism Brain - pathology Humans Maternal immune activation Microglia Microglia - metabolism Neuroinflammation Synaptic pruning Therapy
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