Which one is a better predictor of prognosis in COVID-19: analytical biomarkers or PaO2/FiO2?

Which one is a better predictor of prognosis in COVID-19: analytical biomarkers or PaO2/FiO2?

The study aimed to describe patient characteristics and outcomes by PaO2/FiO2 (PAFI) and degree of inflammation. Retrospective cohort study with data on patients collected from March 1st, 2020 to March 1st, 2023, from the Spanish SEMI-COVID-19 Registry. Non-nosocomial patients with data on PAFI (300...

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Veröffentlicht in:Revista clínica espanõla (English edition) 2025-02, Vol.225 (2), p.57-69
Hauptverfasser: Rubio-Rivas, M., Mora-Luján, J.M., Montero Sáez, A., Martín-Escalante, M.D., Giner Galvañ, V., Maestro de la Calle, G., Taboada Martínez, M.L., Muiño Míguez, A., Lumbreras-Bermejo, C., Antón-Santos, J.-M.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Biomarkers - blood
Cohort Studies
COVID-19
COVID-19 - diagnosis
COVID-19 - mortality
Female
Hospital Mortality
Humans
Inflamación
Inflammation
Male
Middle Aged
Mortalidad
Mortality
PaO2/FiO2
Prognosis
Pronóstico
Retrospective Studies
Risk Factors
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Zusammenfassung:The study aimed to describe patient characteristics and outcomes by PaO2/FiO2 (PAFI) and degree of inflammation. Retrospective cohort study with data on patients collected from March 1st, 2020 to March 1st, 2023, from the Spanish SEMI-COVID-19 Registry. Non-nosocomial patients with data on PAFI (300) who received corticosteroids (CS) for COVID-19 in the first 48 h of admission were included in the study. 5314 patients met the inclusion criteria for the present study. The primary outcome was in-hospital mortality. Higher in-hospital mortality was found in the groups with PAFI 
ISSN:2254-8874
2254-8874
DOI:10.1016/j.rceng.2024.11.003