Characterization of guanidine carboxylases

Guanidine metabolism has been an overlooked aspect of the global nitrogen cycle until RNA sensors (riboswitches) were discovered in bacteria that bind the nitrogen-rich compound. The associated genes were initially proposed to detoxify guanidine from the cells. We were intrigued by a genetic organiz...

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Veröffentlicht in:	Methods in enzymology 2024, Vol.708, p.105-123
Hauptverfasser:	Sinn, M., Techel, J., Joachimi, A., Hartig, J.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Bacterial Proteins - metabolism Carbon-Nitrogen Ligases - genetics Carbon-Nitrogen Ligases - metabolism Enterobacteriaceae - enzymology Enterobacteriaceae - genetics Enterobacteriaceae - metabolism Guanidine Guanidine - chemistry Guanidine - metabolism Guanidine carboxylase Nitrogen assimilation Riboswitch - genetics Substrate Specificity Urea - chemistry Urea - metabolism Urea carboxylase Ureohydrolases - chemistry Ureohydrolases - genetics Ureohydrolases - metabolism
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