Co-Administration of Vitamin U and Antacids in Diets Relieves Gastric Ulcers in Finishing Pigs
One hundred and forty [(Landrace × Yorkshire) × Duroc] barrows and gilts (86.5 ± 1.5 kg) were used in a 28-day experiment in a randomised complete block design. A model of gastric ulcer was established by adding aspirin to the diet or by fasting. The five dietary treatments were TRT1 (basal diet), T...
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creator | Cao, Shanchuan Muniyappan, Madesh Kim, San Kim, In Ho |
description | One hundred and forty [(Landrace × Yorkshire) × Duroc] barrows and gilts (86.5 ± 1.5 kg) were used in a 28-day experiment in a randomised complete block design. A model of gastric ulcer was established by adding aspirin to the diet or by fasting. The five dietary treatments were TRT1 (basal diet), TRT2 (basal diet + fasting), TRT3 (basal diet + 0.05% vitamin U and antacids (VA)), TRT4 (basal diet + aspirin + fasting) and TRT5 (basal diet + aspirin + fasting + 0.1% VA). The active ingredients of VA are vitamin U 50 mg/g, magnesium oxide MgO 60 mg/g, sodium carbonate Na
CO
70 mg/g. The result showed a significant increase in final body weight (p = 0.047) and average daily gain (p = 0.033) in TRT5 compared with TRT1 and TRT2 (p 0.05). The stomach keratinisation score was significantly higher in TRT2 and TRT4 than that in TRT3 (p = 0.032). Stomach keratinisation score decreased from 1.9 to 1.4 in TRT5 compared with TRT4 (p > 0.05). In conclusion, the addition of VA to the diet can improve the degree of gastric ulcer to a certain extent and effectively improve growth performance. |
doi_str_mv | 10.1111/jpn.14073 |
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CO
70 mg/g. The result showed a significant increase in final body weight (p = 0.047) and average daily gain (p = 0.033) in TRT5 compared with TRT1 and TRT2 (p < 0.05). There was no significant difference in carcass scores among treatment groups (p > 0.05). The stomach keratinisation score was significantly higher in TRT2 and TRT4 than that in TRT3 (p = 0.032). Stomach keratinisation score decreased from 1.9 to 1.4 in TRT5 compared with TRT4 (p > 0.05). In conclusion, the addition of VA to the diet can improve the degree of gastric ulcer to a certain extent and effectively improve growth performance.</description><identifier>ISSN: 0931-2439</identifier><identifier>ISSN: 1439-0396</identifier><identifier>EISSN: 1439-0396</identifier><identifier>DOI: 10.1111/jpn.14073</identifier><identifier>PMID: 39569536</identifier><language>eng</language><publisher>Germany</publisher><ispartof>Journal of animal physiology and animal nutrition, 2024-11</ispartof><rights>2024 Wiley‐VCH GmbH. Published by John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c175t-afa043cf6fd9a22c15e8885966949202ba7ed26ca00dffcd530fa6676ae242ac3</cites><orcidid>0000-0002-5724-5098 ; 0000-0002-4677-9350</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39569536$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cao, Shanchuan</creatorcontrib><creatorcontrib>Muniyappan, Madesh</creatorcontrib><creatorcontrib>Kim, San</creatorcontrib><creatorcontrib>Kim, In Ho</creatorcontrib><title>Co-Administration of Vitamin U and Antacids in Diets Relieves Gastric Ulcers in Finishing Pigs</title><title>Journal of animal physiology and animal nutrition</title><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><description>One hundred and forty [(Landrace × Yorkshire) × Duroc] barrows and gilts (86.5 ± 1.5 kg) were used in a 28-day experiment in a randomised complete block design. A model of gastric ulcer was established by adding aspirin to the diet or by fasting. The five dietary treatments were TRT1 (basal diet), TRT2 (basal diet + fasting), TRT3 (basal diet + 0.05% vitamin U and antacids (VA)), TRT4 (basal diet + aspirin + fasting) and TRT5 (basal diet + aspirin + fasting + 0.1% VA). The active ingredients of VA are vitamin U 50 mg/g, magnesium oxide MgO 60 mg/g, sodium carbonate Na
CO
70 mg/g. The result showed a significant increase in final body weight (p = 0.047) and average daily gain (p = 0.033) in TRT5 compared with TRT1 and TRT2 (p < 0.05). There was no significant difference in carcass scores among treatment groups (p > 0.05). The stomach keratinisation score was significantly higher in TRT2 and TRT4 than that in TRT3 (p = 0.032). Stomach keratinisation score decreased from 1.9 to 1.4 in TRT5 compared with TRT4 (p > 0.05). In conclusion, the addition of VA to the diet can improve the degree of gastric ulcer to a certain extent and effectively improve growth performance.</description><issn>0931-2439</issn><issn>1439-0396</issn><issn>1439-0396</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNo9kE1Lw0AQhhdRbK0e_AOyRz2kzu4mm-yxVFuFgiLWo2G6H3VLmtRsKvjv3bbqXAZennkZHkIuGQxZnNvVph6yFHJxRPosFSoBoeQx6YMSLOEx6JGzEFYALM9AnpKeUJlUmZB98j5ukpFZ-9qHrsXONzVtHH3zHcaMzinWho7qDrU3gcbkztsu0BdbeftlA51iPPOazitt2z0w2VV9-HpJn_0ynJMTh1WwF797QOaT-9fxQzJ7mj6OR7NEx5e6BB1CKrSTzijkXLPMFkWRKSlVqjjwBebWcKkRwDinTSbAoZS5RMtTjloMyPWhd9M2n1sbunLtg7ZVhbVttqEUTLAMeAEQ0ZsDqtsmhNa6ctP6NbbfJYNyp7OMOsu9zshe_dZuF2tr_sk_f-IHSkdwDw</recordid><startdate>20241121</startdate><enddate>20241121</enddate><creator>Cao, Shanchuan</creator><creator>Muniyappan, Madesh</creator><creator>Kim, San</creator><creator>Kim, In Ho</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5724-5098</orcidid><orcidid>https://orcid.org/0000-0002-4677-9350</orcidid></search><sort><creationdate>20241121</creationdate><title>Co-Administration of Vitamin U and Antacids in Diets Relieves Gastric Ulcers in Finishing Pigs</title><author>Cao, Shanchuan ; Muniyappan, Madesh ; Kim, San ; Kim, In Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c175t-afa043cf6fd9a22c15e8885966949202ba7ed26ca00dffcd530fa6676ae242ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cao, Shanchuan</creatorcontrib><creatorcontrib>Muniyappan, Madesh</creatorcontrib><creatorcontrib>Kim, San</creatorcontrib><creatorcontrib>Kim, In Ho</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of animal physiology and animal nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cao, Shanchuan</au><au>Muniyappan, Madesh</au><au>Kim, San</au><au>Kim, In Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Co-Administration of Vitamin U and Antacids in Diets Relieves Gastric Ulcers in Finishing Pigs</atitle><jtitle>Journal of animal physiology and animal nutrition</jtitle><addtitle>J Anim Physiol Anim Nutr (Berl)</addtitle><date>2024-11-21</date><risdate>2024</risdate><issn>0931-2439</issn><issn>1439-0396</issn><eissn>1439-0396</eissn><abstract>One hundred and forty [(Landrace × Yorkshire) × Duroc] barrows and gilts (86.5 ± 1.5 kg) were used in a 28-day experiment in a randomised complete block design. A model of gastric ulcer was established by adding aspirin to the diet or by fasting. The five dietary treatments were TRT1 (basal diet), TRT2 (basal diet + fasting), TRT3 (basal diet + 0.05% vitamin U and antacids (VA)), TRT4 (basal diet + aspirin + fasting) and TRT5 (basal diet + aspirin + fasting + 0.1% VA). The active ingredients of VA are vitamin U 50 mg/g, magnesium oxide MgO 60 mg/g, sodium carbonate Na
CO
70 mg/g. The result showed a significant increase in final body weight (p = 0.047) and average daily gain (p = 0.033) in TRT5 compared with TRT1 and TRT2 (p < 0.05). There was no significant difference in carcass scores among treatment groups (p > 0.05). The stomach keratinisation score was significantly higher in TRT2 and TRT4 than that in TRT3 (p = 0.032). Stomach keratinisation score decreased from 1.9 to 1.4 in TRT5 compared with TRT4 (p > 0.05). In conclusion, the addition of VA to the diet can improve the degree of gastric ulcer to a certain extent and effectively improve growth performance.</abstract><cop>Germany</cop><pmid>39569536</pmid><doi>10.1111/jpn.14073</doi><orcidid>https://orcid.org/0000-0002-5724-5098</orcidid><orcidid>https://orcid.org/0000-0002-4677-9350</orcidid></addata></record> |
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title | Co-Administration of Vitamin U and Antacids in Diets Relieves Gastric Ulcers in Finishing Pigs |
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