Rational construction of porous cobalt nanoparticle integrated nitrogen doped hollow carbon nanostructures for peptide agonist exendin-4 biosensing

In this study, we designed a point-of-care (POC) testing electrochemical biosensor using an integrated biosensing assay based on hollow-like nitrogen-doped carbon nanostructures combined with cobalt nanoparticles (Co@HNCNs, Co3O4@HNCNs, and CoP@HNCNs). These are functionalized with Anti-Exendin-4 An...

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Veröffentlicht in:	Biosensors & bioelectronics 2025-02, Vol.270, p.116938, Article 116938
Hauptverfasser:	Zhang, Wei, Natarajan, Bharathi, Kannan, Palanisamy, Medlín, Rostislav, Nicolai, Laurent Christophe, Procházka, Michal, Minar, Jan, Subramanian, Palaniappan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Immobilized - chemistry Antibodies, Immobilized - immunology Biosensing Techniques - methods Biosensor Carbon - chemistry Clinical analysis Cobalt - chemistry Cobalt nanoparticles Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - urine Electrochemical Techniques - methods Exenatide - blood Exenatide - chemistry Exendin-4 Hollow carbon nanostructures Humans Limit of Detection Metal Nanoparticles - chemistry Nanostructures - chemistry Nitrogen - chemistry Nitrogen doping Porosity Real samples
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