ER + HER2- early-stage breast cancer: association of HER2 expression, tumor characteristics, and outcomes

Purpose To evaluate the association between the HER2 score as provided by the Oncotype DX Recurrence Score (RS) assay, tumor characteristics, and outcomes in early-stage, ER + HER2-negative breast cancer (BC). Methods All women insured by the Clalit Health Services, with early-stage, ER + HER2-negat...

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Veröffentlicht in:	Breast cancer research and treatment 2025-02, Vol.210 (1), p.167-177
Hauptverfasser:	Goldvaser, Hadar, Yerushalmi, Rinat, Mutai, Raz, Kuchuk, Iryna, Toker, Margarita, Paluch-Shimon, Shani, Drumea, Karen, Evron, Ella, Sonnenblick, Amir, Gal-Yam, Einav, Sela, Gil Bar, Shai, Ayelet, Merose, Rotem, Bareket-Samish, Avital, Soussan-Gutman, Lior, Stemmer, Salomon M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - metabolism Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Clinical outcomes Cohort analysis ErbB-2 protein Female Gene Expression Profiling Humans Kaplan-Meier Estimate Medicine Medicine & Public Health Middle Aged Neoplasm Recurrence, Local - pathology Neoplasm Staging Oncology Prognosis Receptor, ErbB-2 - metabolism Receptors, Estrogen - metabolism Survival Survival analysis Tumors
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