Multi-omics joint analysis reveals the mechanism underlying Chinese herbal Yougui Pill in the treatment of knee osteoarthritis

Yougui Pill (YGP), originating from Jingyue Quanshu, comprises 10 traditional Chinese medicines (TCMs). This classic prescription is renowned for its ability to tonify the kidney, warm the kidney, promote yang, warm the interior, and dispel cold. YGP has proven effective in treating degenerative kne...

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Veröffentlicht in:	Journal of ethnopharmacology 2025-02, Vol.338 (Pt 3), p.119098, Article 119098
Hauptverfasser:	Li, Siyu, Yang, Yongju, Zhang, Yu, He, Fanyu, Chen, Jie, Fan, Yuanhe, Zhang, Hui, Guan, Xuefeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, High Pressure Liquid Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - pharmacology Knee osteoarthritis Male Metabolomics Multiomics Osteoarthritis, Knee - drug therapy Osteoarthritis, Knee - metabolism Rats Rats, Sprague-Dawley Signal Transduction - drug effects Tandem Mass Spectrometry Transcriptomics Yougui pill
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