C-C motif chemokine receptor-2 blockade ameliorates pulmonary hypertension in rats and synergizes with a pulmonary vasodilator

We investigated whether the disruption of C-C motif chemokine receptor (CCR) 2 may attenuate the development of pulmonary arterial hypertension (PAH) in any rat models with the reversal of the associated pro-inflammatory state and vascular dysfunction, and synergize with a conventional pulmonary vas...

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Veröffentlicht in:Cardiovascular research 2024-11
Hauptverfasser: Tsuboya, Naoki, Sawada, Hirofumi, Mitani, Yoshihide, Oshita, Hironori, Ohya, Kazunobu, Takeoka, Mami, Kabwe, Jane Chanda, Miyasaka, Yoshiki, Ito, Hiromasa, Yodoya, Noriko, Ohashi, Hiroyuki, Maruyama, Junko, Okamoto, Ryuji, Mashimo, Tomoji, Dohi, Kaoru, Nishimura, Yuhei, Maruyama, Kazuo, Hirayama, Masahiro
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Sprache:eng
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