If you can’t beat them, join them: Anti-CRISPR proteins derived from CRISPR-associated genes

Bacteriophages have evolved numerous mechanisms to evade targeting by CRISPR-Cas defense systems. However, the evolutionary origin of these so-called “anti-CRISPRs” remains poorly understood. In a recent issue of Nature, Katz et al.1 provide evidence that some anti-CRISPRs were derived from genes of...

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Veröffentlicht in:	Cell host & microbe 2024-11, Vol.32 (11), p.1871-1873
1. Verfasser:	Mo, Charlie Y.
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description	Bacteriophages have evolved numerous mechanisms to evade targeting by CRISPR-Cas defense systems. However, the evolutionary origin of these so-called “anti-CRISPRs” remains poorly understood. In a recent issue of Nature, Katz et al.1 provide evidence that some anti-CRISPRs were derived from genes of the CRISPR-Cas systems themselves. Bacteriophages have evolved numerous mechanisms to evade targeting by CRISPR-Cas defense systems. However, the evolutionary origin of these so-called “anti-CRISPRs” remains poorly understood. In a recent issue of Nature, Katz et al. provide evidence that some anti-CRISPRs were derived from genes of the CRISPR-Cas systems themselves.
doi_str_mv	10.1016/j.chom.2024.10.009
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title	If you can’t beat them, join them: Anti-CRISPR proteins derived from CRISPR-associated genes
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