White matter aging and its impact on brain function

Aging has a detrimental impact on white matter, resulting in reduced volume, compromised structural integrity of myelinated axons, and an increase in white matter hyperintensities. These changes are closely linked to cognitive decline and neurological disabilities. The deterioration of myelin and it...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2025-01, Vol.113 (1), p.127-139
Hauptverfasser:	Groh, Janos, Simons, Mikael
Format:	Artikel
Sprache:	eng
Schlagworte:	aging Aging - physiology Animals Brain - physiology Humans myelin Myelin Sheath - physiology neuroinflammation white matter White Matter - pathology
Online-Zugang:	Volltext
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