Grading Melanocytic Dysplasia: Updated Histopathologic Criteria

Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of cutaneous pathology 2024-11
Hauptverfasser: Shea, Christopher R, Prieto, Victor G, Shachaf, Catherine M, Florell, Scott R
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title Journal of cutaneous pathology
container_volume
creator Shea, Christopher R
Prieto, Victor G
Shachaf, Catherine M
Florell, Scott R
description Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and architectural elements of the Duke grading system to facilitate more detailed and precise assessment of dysplastic nevi.
doi_str_mv 10.1111/cup.14744
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_3128761407</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3128761407</sourcerecordid><originalsourceid>FETCH-LOGICAL-c175t-1f65e477fcf867dbc4ed8b733ffcf1a6d022bab72757bf00f88adfe2d6ab48fa3</originalsourceid><addsrcrecordid>eNo9kD1PwzAURS0EoqUw8AdQRhhS7NixXRaECrRIRSx0tvxZjNIm2M6Qf4-hhbdc6eno6uoAcIngFOW71X03RYQRcgTGiEJYwprCYzCGGOKSzjgbgbMYPyFElNP6FIzwrMYVndExuF8EafxuU7zaRu5aPSSvi8chdo2MXt4V687IZE2x9DG1nUwfbdNuMjIPPtng5Tk4cbKJ9uKQE7B-fnqfL8vV2-Jl_rAqNWJ1KpGjtSWMOe04ZUZpYg1XDGOXP0hSA6tKScUqVjPlIHScS-NsZahUhDuJJ-B639uF9qu3MYmtj9o2ebRt-ygwqjijiECW0Zs9qkMbY7BOdMFvZRgEguLHl8i-xK-vzF4danu1teaf_BOEvwEP4mbu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3128761407</pqid></control><display><type>article</type><title>Grading Melanocytic Dysplasia: Updated Histopathologic Criteria</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Shea, Christopher R ; Prieto, Victor G ; Shachaf, Catherine M ; Florell, Scott R</creator><creatorcontrib>Shea, Christopher R ; Prieto, Victor G ; Shachaf, Catherine M ; Florell, Scott R</creatorcontrib><description>Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and architectural elements of the Duke grading system to facilitate more detailed and precise assessment of dysplastic nevi.</description><identifier>ISSN: 0303-6987</identifier><identifier>ISSN: 1600-0560</identifier><identifier>EISSN: 1600-0560</identifier><identifier>DOI: 10.1111/cup.14744</identifier><identifier>PMID: 39532696</identifier><language>eng</language><publisher>United States</publisher><ispartof>Journal of cutaneous pathology, 2024-11</ispartof><rights>2024 The Author(s). Journal of Cutaneous Pathology published by John Wiley &amp; Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c175t-1f65e477fcf867dbc4ed8b733ffcf1a6d022bab72757bf00f88adfe2d6ab48fa3</cites><orcidid>0000-0002-3780-8113 ; 0000-0001-9204-7161</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39532696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shea, Christopher R</creatorcontrib><creatorcontrib>Prieto, Victor G</creatorcontrib><creatorcontrib>Shachaf, Catherine M</creatorcontrib><creatorcontrib>Florell, Scott R</creatorcontrib><title>Grading Melanocytic Dysplasia: Updated Histopathologic Criteria</title><title>Journal of cutaneous pathology</title><addtitle>J Cutan Pathol</addtitle><description>Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and architectural elements of the Duke grading system to facilitate more detailed and precise assessment of dysplastic nevi.</description><issn>0303-6987</issn><issn>1600-0560</issn><issn>1600-0560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNo9kD1PwzAURS0EoqUw8AdQRhhS7NixXRaECrRIRSx0tvxZjNIm2M6Qf4-hhbdc6eno6uoAcIngFOW71X03RYQRcgTGiEJYwprCYzCGGOKSzjgbgbMYPyFElNP6FIzwrMYVndExuF8EafxuU7zaRu5aPSSvi8chdo2MXt4V687IZE2x9DG1nUwfbdNuMjIPPtng5Tk4cbKJ9uKQE7B-fnqfL8vV2-Jl_rAqNWJ1KpGjtSWMOe04ZUZpYg1XDGOXP0hSA6tKScUqVjPlIHScS-NsZahUhDuJJ-B639uF9qu3MYmtj9o2ebRt-ygwqjijiECW0Zs9qkMbY7BOdMFvZRgEguLHl8i-xK-vzF4danu1teaf_BOEvwEP4mbu</recordid><startdate>20241112</startdate><enddate>20241112</enddate><creator>Shea, Christopher R</creator><creator>Prieto, Victor G</creator><creator>Shachaf, Catherine M</creator><creator>Florell, Scott R</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3780-8113</orcidid><orcidid>https://orcid.org/0000-0001-9204-7161</orcidid></search><sort><creationdate>20241112</creationdate><title>Grading Melanocytic Dysplasia: Updated Histopathologic Criteria</title><author>Shea, Christopher R ; Prieto, Victor G ; Shachaf, Catherine M ; Florell, Scott R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c175t-1f65e477fcf867dbc4ed8b733ffcf1a6d022bab72757bf00f88adfe2d6ab48fa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shea, Christopher R</creatorcontrib><creatorcontrib>Prieto, Victor G</creatorcontrib><creatorcontrib>Shachaf, Catherine M</creatorcontrib><creatorcontrib>Florell, Scott R</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cutaneous pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shea, Christopher R</au><au>Prieto, Victor G</au><au>Shachaf, Catherine M</au><au>Florell, Scott R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Grading Melanocytic Dysplasia: Updated Histopathologic Criteria</atitle><jtitle>Journal of cutaneous pathology</jtitle><addtitle>J Cutan Pathol</addtitle><date>2024-11-12</date><risdate>2024</risdate><issn>0303-6987</issn><issn>1600-0560</issn><eissn>1600-0560</eissn><abstract>Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO-C). WHO-C presents a dichotomous classification (high-grade versus low-grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement. The Duke classification is a related approach that provides mostly quantitative histopathologic criteria for dysplastic nevi and gives due weight to architectural features as well as cytology. This paper proposes and illustrates updated criteria for scoring and grading melanocytic dysplasia, incorporating some of the definitions and categories of WHO-C, while refining the quantitative and architectural elements of the Duke grading system to facilitate more detailed and precise assessment of dysplastic nevi.</abstract><cop>United States</cop><pmid>39532696</pmid><doi>10.1111/cup.14744</doi><orcidid>https://orcid.org/0000-0002-3780-8113</orcidid><orcidid>https://orcid.org/0000-0001-9204-7161</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0303-6987
ispartof Journal of cutaneous pathology, 2024-11
issn 0303-6987
1600-0560
1600-0560
language eng
recordid cdi_proquest_miscellaneous_3128761407
source Wiley Online Library Journals Frontfile Complete
title Grading Melanocytic Dysplasia: Updated Histopathologic Criteria
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T14%3A57%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Grading%20Melanocytic%20Dysplasia:%20Updated%20Histopathologic%20Criteria&rft.jtitle=Journal%20of%20cutaneous%20pathology&rft.au=Shea,%20Christopher%20R&rft.date=2024-11-12&rft.issn=0303-6987&rft.eissn=1600-0560&rft_id=info:doi/10.1111/cup.14744&rft_dat=%3Cproquest_cross%3E3128761407%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3128761407&rft_id=info:pmid/39532696&rfr_iscdi=true