In vitro monitoring of drug resistance emergence during stepwise induction of bedaquiline and clofazimine, alone and in combination: a phenotypic and genotypic analysis

The co-resistance between bedaquiline and clofazimine raises significant concerns, as they are commonly co-administered as core drugs in drug-resistant TB regimens. The present study aimed to monitor drug resistance-associated gene mutations and the phenotypic change in Mycobacterium tuberculosis (M...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2024-11
Hauptverfasser: Chen, Suting, Shang, Yuanyuan, Zheng, Jifang, Huo, Fengmin, Xue, Yi, Zhao, Liping, Jiang, Guanglu, Chu, Naihui, Huang, Hairong
Format: Artikel
Sprache:eng
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