Temporospatial control of topoisomerases by essential cellular processes

Topoisomerases are essential, ubiquitous enzymes that break and rejoin the DNA strand to control supercoiling. Because topoisomerases are DNA scissors, these enzymes are highly regulated to avoid excessive DNA cleavage, a vulnerability exploited by many antibiotics. Topoisomerase activity must be co...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in microbiology 2024-12, Vol.82, p.102559, Article 102559
Hauptverfasser:	Kim, Sora, Guo, Monica S
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - enzymology Bacteria - genetics Bacteria - metabolism Cell Division DNA Gyrase - genetics DNA Gyrase - metabolism DNA Replication DNA Topoisomerases - genetics DNA Topoisomerases - metabolism Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli - metabolism Gene Expression Regulation, Bacterial
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!