Manganese-Mediated Cascade Radical Oxidative Cyclization/1,6-Conjugate Addition of Unsaturated Oximes with p-Quinone Methides: Facile Access to β,β-Diarylmethine Substituted Isoxazolines

A simple and efficient strategy for the synthesis of structurally diverse β,β-diarylmethine substituted isoxazoline derivatives have been developed. This approach employs a manganese-promoted oxidative cyclization coupled with a 1,6-conjugate addition of unsaturated oximes to p-quinone methides. The...

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Veröffentlicht in:Chemistry, an Asian journal an Asian journal, 2024-11, p.e202401079
Hauptverfasser: Vara, Vijay, Thete, Kishor R, Ghotekar, Ganesh S, Muthukrishnan, M
Format: Artikel
Sprache:eng
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