Wen-Shen-Tong-Luo-Zhi-Tong-Decoction inhibits bone loss in senile osteoporosis model mice by promoting testosterone production

Wen-Shen-Tong-Luo-Zhi-Tong-Decoction (WSTLZTD) is a traditional Chinese medicine formula, and its effectiveness in the treatment of senile osteoporosis(SOP) has been confirmed by clinical studies. However, the underlying mechanism of WSTLZTD in SOP is unclear. This study aimed to clarify the unique...

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Veröffentlicht in:	Journal of ethnopharmacology 2025-02, Vol.338 (Pt 2), p.119033, Article 119033
Hauptverfasser:	Li, Muzhe, Niu, Yuanyuan, Zhang, Tianchi, Yang, Haomiao, Tian, Linkun, Zhou, Shijie, Wumiti, Taxi, Sun, Jie, Zhou, Qinfeng, Zuo, Xinchen, Gao, Tianle, Li, Jiale, Ma, Yong, Guo, Yang, Wang, Lining
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cellular Senescence - drug effects Disease Models, Animal Drugs, Chinese Herbal - pharmacology Energy Metabolism - drug effects Male Mesenchymal Stem Cells - drug effects Mice Mitochondria - drug effects Mitochondria - metabolism Mitochondrial energy metabolism Osteogenesis - drug effects Osteoporosis - drug therapy Senile osteoporosis Testis - drug effects Testis - metabolism Testis - pathology Testosterone Testosterone - blood Traditional Chinese medicine Wen-Shen-Tong-Luo-Zhi-Tong-Decoction
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