Dietary regulation of silent synapses in the dorsolateral striatum

•High fat diet upregulates silent synapses in the dorsolateral striatum.•High fat diet induced changes in silent synapses occur over an extended period.•High fat diet induces a loss of stubby spines in the indirect pathway. Obesity and drugs of abuse share overlapping neural circuits and behaviors....

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Veröffentlicht in:	Neuroscience 2024-12, Vol.563, p.43-50
Hauptverfasser:	Meyers, Allison M., Gnazzo, Federico G., Barrera, Eddy D., Nabatian, Tikva, Chan, Larry, Beeler, Jeff A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addiction Animals Corpus Striatum - drug effects Corpus Striatum - metabolism Diet, High-Fat - adverse effects Dorsolateral striatum High fat diet Male Mice Mice, Inbred C57BL Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Neurons - metabolism Neurons - physiology Obesity Obesity - metabolism Obesity - physiopathology Silent synapses Synapses - physiology
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