Local antimicrobial delivery systems for prophylaxis and treatment of periprosthetic traumatological infections

Infections associated with implants are the most serious complications in joint replacement surgeries and can jeopardize the functionality of orthopedic implants. Local antimicrobial delivery could enable antibiotics to attain concentrations above the minimum inhibitory concentration (MIC) threshold...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2025-01, Vol.204, p.106940, Article 106940
Hauptverfasser:	Aparicio-Blanco, Juan, López-Torres, Irene I., Alonso-Berenguel, María, Torres-Suárez, Ana I., Martín-Sabroso, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Infective Agents - administration & dosage Anti-Infective Agents - therapeutic use Antibiotics Biofilm Bone cement Drug Delivery Systems - methods Humans Implant coating Joint replacement Local drug delivery Prosthesis-Related Infections - drug therapy Prosthesis-Related Infections - prevention & control
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