Intranasal Premedication With Dexmedetomidine in an Adult Patient With Intellectual Disabilities: A Case Report
Recently, intranasal dexmedetomidine (DEX) has been reported to be effective as a preanesthetic medication, mostly in healthy pediatric patients. We attempted to administer intranasal DEX premedication in this case to an adult patient with intellectual disability who previously had difficulty tolera...
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| Veröffentlicht in: | Anesthesia progress 2024-09, Vol.71 (3), p.147-148 |
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| container_end_page | 148 |
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| container_issue | 3 |
| container_start_page | 147 |
| container_title | Anesthesia progress |
| container_volume | 71 |
| creator | Tanaka, Jotaro Miyake, Saki Fujimoto, Maki Nishioka, Yukiko Higuchi, Hitoshi Miyawaki, Takuya |
| description | Recently, intranasal dexmedetomidine (DEX) has been reported to be effective as a preanesthetic medication, mostly in healthy pediatric patients. We attempted to administer intranasal DEX premedication in this case to an adult patient with intellectual disability who previously had difficulty tolerating premedication with oral midazolam. Using an intranasal atomization delivery device (MAD Nasal, Teleflex), we administered 1.5 µg/kg of DEX intranasally and were able to achieve adequate sedation, which facilitated a smooth mask induction of general anesthesia with sevoflurane. Premedication with intranasal DEX may be a useful method for enabling induction of general anesthesia in adult patients with intellectual disabilities. |
| doi_str_mv | 10.2344/anpr-23-0057 |
| format | Article |
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Premedication with intranasal DEX may be a useful method for enabling induction of general anesthesia in adult patients with intellectual disabilities.</description><subject>Administration, Intranasal</subject><subject>Adult</subject><subject>Anesthesia, General</subject><subject>Anesthetics, Inhalation - administration & dosage</subject><subject>Dexmedetomidine - administration & dosage</subject><subject>Humans</subject><subject>Hypnotics and Sedatives - administration & dosage</subject><subject>Intellectual Disability - complications</subject><subject>Male</subject><subject>Nebulizers and Vaporizers</subject><subject>Preanesthetic Medication</subject><subject>Premedication</subject><subject>Sevoflurane - administration & dosage</subject><issn>0003-3006</issn><issn>1878-7177</issn><issn>1878-7177</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM9LwzAUgIMoOqc3z5KjB6svTdqk3sbmj8HAIQOPJW1fMdKmM0lB_3szNj3lkffx8fgIuWJwl3Ih7rXduiTlCUAmj8iEKakSyaQ8JhMA4AkHyM_IufefAExAKk7JGS8y4IwXEzIsbXDaaq87unbYY2NqHcxg6bsJH3SB3_ELw9CbxlikxlJt6awZu0DXkUMb9mDUYNdhHcYoWhivK9OZuPcPdEbn2iN9w-3gwgU5aXXn8fLwTsnm6XEzf0lWr8_L-WyV1AUvkgryulEIOWOqaFueMZUx3WJT5UKnUKtKSQlYQKEVKlXLXDSqFYxJyEBkFZ-Sm71264avEX0oe-PreKG2OIy-5CwVeZGCYhG93aO1G7x32JZbZ3rtfkoG5a5wuSscp3JXOOLXB_NYxTT_8F9S_guEd3dP</recordid><startdate>20240909</startdate><enddate>20240909</enddate><creator>Tanaka, Jotaro</creator><creator>Miyake, Saki</creator><creator>Fujimoto, Maki</creator><creator>Nishioka, Yukiko</creator><creator>Higuchi, Hitoshi</creator><creator>Miyawaki, Takuya</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20240909</creationdate><title>Intranasal Premedication With Dexmedetomidine in an Adult Patient With Intellectual Disabilities: A Case Report</title><author>Tanaka, Jotaro ; Miyake, Saki ; Fujimoto, Maki ; Nishioka, Yukiko ; Higuchi, Hitoshi ; Miyawaki, Takuya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c939-b06cd8e061189ff351851afedb64a20c8b8770e909a8e88c764d8f411705045b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Administration, Intranasal</topic><topic>Adult</topic><topic>Anesthesia, General</topic><topic>Anesthetics, Inhalation - administration & dosage</topic><topic>Dexmedetomidine - administration & dosage</topic><topic>Humans</topic><topic>Hypnotics and Sedatives - administration & dosage</topic><topic>Intellectual Disability - complications</topic><topic>Male</topic><topic>Nebulizers and Vaporizers</topic><topic>Preanesthetic Medication</topic><topic>Premedication</topic><topic>Sevoflurane - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tanaka, Jotaro</creatorcontrib><creatorcontrib>Miyake, Saki</creatorcontrib><creatorcontrib>Fujimoto, Maki</creatorcontrib><creatorcontrib>Nishioka, Yukiko</creatorcontrib><creatorcontrib>Higuchi, Hitoshi</creatorcontrib><creatorcontrib>Miyawaki, Takuya</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesia progress</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tanaka, Jotaro</au><au>Miyake, Saki</au><au>Fujimoto, Maki</au><au>Nishioka, Yukiko</au><au>Higuchi, Hitoshi</au><au>Miyawaki, Takuya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intranasal Premedication With Dexmedetomidine in an Adult Patient With Intellectual Disabilities: A Case Report</atitle><jtitle>Anesthesia progress</jtitle><addtitle>Anesth Prog</addtitle><date>2024-09-09</date><risdate>2024</risdate><volume>71</volume><issue>3</issue><spage>147</spage><epage>148</epage><pages>147-148</pages><issn>0003-3006</issn><issn>1878-7177</issn><eissn>1878-7177</eissn><abstract>Recently, intranasal dexmedetomidine (DEX) has been reported to be effective as a preanesthetic medication, mostly in healthy pediatric patients. 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| ispartof | Anesthesia progress, 2024-09, Vol.71 (3), p.147-148 |
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| source | MEDLINE; Free E- Journals |
| subjects | Administration, Intranasal Adult Anesthesia, General Anesthetics, Inhalation - administration & dosage Dexmedetomidine - administration & dosage Humans Hypnotics and Sedatives - administration & dosage Intellectual Disability - complications Male Nebulizers and Vaporizers Preanesthetic Medication Premedication Sevoflurane - administration & dosage |
| title | Intranasal Premedication With Dexmedetomidine in an Adult Patient With Intellectual Disabilities: A Case Report |
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