Design, synthesis, biological evaluation, and in silico studies of novel N-substituted-2-(3,4,5-trimethoxyphenyl)-1H-benzodimidazole-6-carboxamides as promising anticancer agents

Novel benzimidazole-based derivatives were synthesized and their cytotoxic activities were evaluated against two human cancer cells, SW480 and A549, and the normal human MRC-5 cells, using the MTT assay. N-(2,4-Dimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamide (5o) showe...

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Veröffentlicht in:	RSC advances 2024-11, Vol.14 (48), p.35323
Hauptverfasser:	Dastyafteh, Navid, Negahdaripour, Manica, Sayahi, Mohammad Hosein, Emami, Mina, Ghasemi, Younes, Safaei, Elham, Azizian, Homa, Pakrouh Jahromi, Zahra, Asadi, Mehdi, Mohajeri-Tehrani, Mohammad Reza, Zare, Fateme, Shahidi, Minoo, Pooraskari, Zahra, Sajjadi-Jazi, Sayed Mahmoud, Larijani, Bagher, Mahdavi, Mohammad, Ranjbar, Sara
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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