Oligodendrocyte Slc48a1 (Hrg1) encodes a functional heme transporter required for myelin integrity

Oligodendrocytes (OLs) of the central nervous system require iron for proteolipid biosynthesis during the myelination process. Although most heme is found complexed to hemoglobin in red blood cells, surprisingly, we found that Slc48a1, encoding the heme transporter Hrg1, is expressed at higher level...

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