Tissue nano-transfection of antimicrobial genes drives bacterial biofilm killing in wounds and is potentially mediated by extracellular vesicles

The emergence of bacteria that are resistant to antibiotics is on track to become a major global health crisis. Therefore, there is an urgent need for new treatment options. Here, we studied the implementation of tissue-nanotransfection (TNT) to treat Staphylococcus aureus-infected wounds by deliver...

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Veröffentlicht in:Journal of controlled release 2024-12, Vol.376, p.1300-1315
Hauptverfasser: Cuellar-Gaviria, Tatiana Z., Rincon-Benavides, Maria Angelica, Halipci Topsakal, Hatice Nur, Salazar-Puerta, Ana Isabel, Jaramillo-Garrido, Shara, Kordowski, Mia, Vasquez-Martinez, Carlos A., Nguyen, Kim Truc, Rima, Xilal Y., Rana, Pranav S.J.B., Combita-Heredia, Orlando, Deng, Binbin, Dathathreya, Kavya, McComb, David W., Reategui, Eduardo, Wozniak, Daniel, Higuita-Castro, Natalia, Gallego-Perez, Daniel
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Sprache:eng
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