PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca2+/Calpain/YAP pathway

The significance of physical factors in the onset and progression of tumors has been increasingly substantiated by a multitude of studies. The extracellular matrix, a pivotal component of the tumor microenvironment, has been the subject of extensive investigation in connection with the advancement o...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular cell research 2025-01, Vol.1872 (1), p.119871, Article 119871
Hauptverfasser:	Zhu, Biqiang, Li, Fan, Yu, Jiajun, Liang, Zhulin, Ke, Xinwen, Wang, Yong, Song, Zhengshuai, Li, Zhongyuan, Li, Guohao, Guo, Yonglian
Format:	Artikel
Sprache:	eng
Schlagworte:	Calpain Kidney renal clear cell carcinoma Matrix stiffness PIEZO1 YAP
Online-Zugang:	Volltext
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