Sensitivity evaluation of an optical microfiber featuring interfaces with various gold nanoparticle morphologies: Application to the GFAP detection

Glial fibrillary acidic protein (GFAP) is a specific blood biomarker for various neurological diseases, including traumatic brain injury (TBI). In this study, we present a cost-effective, portable, and label-free biosensing method for the sensitive and rapid detection of GFAP in body fluids. As the...

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Veröffentlicht in:	Biosensors & bioelectronics 2025-01, Vol.268, p.116901, Article 116901
Hauptverfasser:	Xiao, Aoxiang, Wu, Xiaolan, Zheng, Jiaying, Huang, Yunyun, Xu, Anding, Guan, Bai-Ou
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarkers Biosensing Techniques - instrumentation Biosensing Techniques - methods biosensors blood serum brain damage Brain Injuries, Traumatic - blood cerebrospinal fluid cost effectiveness detection limit Early detection early diagnosis Equipment Design Glial fibrillary acidic protein Glial Fibrillary Acidic Protein - analysis Glial Fibrillary Acidic Protein - blood gold Gold - chemistry Humans Immune sensor Limit of Detection Metal Nanoparticles - chemistry nanogold Optical Fibers Optical microfiber biosensor phosphates Plasmonic rapid methods
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