Alternative polyadenylation shapes the molecular and clinical features of lung adenocarcinoma

Alternative polyadenylation (APA) is a major mechanism of post-transcriptional regulation that affects mRNA stability, localization and translation efficiency. Previous pan-cancer studies have revealed that APA is frequently disrupted in cancer and is associated with patient outcomes. Yet, little is...

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Veröffentlicht in:	Human molecular genetics 2024-11
Hauptverfasser:	Gao, Yipeng, Shaw, Vikram R, Amos, Christopher I
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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