Profiling Cysteine Proteases Activities in Neuroinflammatory Cells

A new activity-based probe (ABP) of cysteine proteases (FGA139) has been designed and synthesized. The design of the ABP has been done based upon the chemical structure of an irreversible inhibitor of cysteine proteases by attaching a bodipy fluorophore at the N-terminus of the peptide backbone. The...

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Veröffentlicht in:ChemMedChem 2024-11, p.e202400520
Hauptverfasser: Agost-Beltrán, Laura, Canseco-Rodríguez, Ania, Schirmeister, Tanja, Rodríguez, Santiago, Sánchez-Pérez, Ana María, González, Florenci V
Format: Artikel
Sprache:eng
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