Metformin boosts doxorubicin efficacy and increases CD8 + T cell frequency in mouse breast cancer

Breast cancer is a leading cause of cancer-related deaths among women worldwide. The presence and function of CD8 + T cells in the tumor microenvironment have been associated with better patient outcomes. Drug toxicity has posed a significant challenge to the clinical implementation of chemotherapy-...

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Veröffentlicht in:Clinical & translational oncology 2024-10
Hauptverfasser: Hassani, Elaheh, Mozzendizaji, Sahand, Shafiei-Irannejad, Vahid, Mohammadzadeh, Adel
Format: Artikel
Sprache:eng
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