Cryo-EM structures of the zinc transporters ZnT3 and ZnT4 provide insights into their transport mechanisms

Zinc transporters (ZnTs) act as H /Zn antiporters, crucial for zinc homeostasis. Brain-specific ZnT3 expressed in synaptic vesicles transports Zn from the cytosol into vesicles and is essential for neurotransmission, with ZnT3 dysfunction associated with neurological disorders. Ubiquitously expresse...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	FEBS letters 2024-10
Hauptverfasser:	Ishida, Hanako, Yo, Riri, Zhang, Zhikuan, Shimizu, Toshiyuki, Ohto, Umeharu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!