Capturing the mechanosensitivity of cell proliferation in models of epithelium

Despite the primary role of cell proliferation in tissue development and homeostatic maintenance, the interplay between cell density, cell mechanoresponse, and cell growth and division is not yet understood. In this article, we address this issue by reporting on an experimental investigation of cell...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2024-11, Vol.121 (45), p.e2308126121
Hauptverfasser:	Höllring, Kevin, Nuić, Lovro, Rogić, Luka, Kaliman, Sara, Gehrer, Simone, Wollnik, Carina, Rehfeldt, Florian, Hubert, Maxime, Smith, Ana-Sunčana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell culture Cell cycle Cell Cycle - physiology Cell density Cell division Cell Division - physiology Cell growth Cell proliferation Cell Proliferation - physiology Data analysis Density Epithelium Epithelium - physiology Formability Glass substrates Mechanotransduction, Cellular - physiology Models, Biological Time dependence Tissues
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