Clinical features and risk factors of cholestasis in small for gestational age preterm infants

To investigate the clinical features and risk factors of cholestasis in small for gestational age (SGA) preterm infants. This study selected SGA preterm infants born at less than 37 weeks of gestation and admitted to the Department of Neonatology, Children's Hospital of Soochow Universitywithin...

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Veröffentlicht in:Zhongguo dang dai er ke za zhi 2024-10, Vol.26 (10), p.1027
Hauptverfasser: Chen, Yu, Zhu, Xue-Ping
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description To investigate the clinical features and risk factors of cholestasis in small for gestational age (SGA) preterm infants. This study selected SGA preterm infants born at less than 37 weeks of gestation and admitted to the Department of Neonatology, Children's Hospital of Soochow Universitywithin 24 hours after birth. The infants were divided into two groups: a cholestasis group and a non-cholestasis group. Clinical data from July 2017 to June 2022 were collected and retrospectively analyzed. Among the 553 SGA preterm infants included, 100 infants (18.1%) developed cholestasis. The incidence rates in different gestational age and birth weight groups were as follows: extremely preterm infants 50.0%, very preterm infants 46.6%, moderate preterm infants 32.7%, and late preterm infants 9.8%; birth weight (BW)
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This study selected SGA preterm infants born at less than 37 weeks of gestation and admitted to the Department of Neonatology, Children's Hospital of Soochow Universitywithin 24 hours after birth. The infants were divided into two groups: a cholestasis group and a non-cholestasis group. Clinical data from July 2017 to June 2022 were collected and retrospectively analyzed. Among the 553 SGA preterm infants included, 100 infants (18.1%) developed cholestasis. The incidence rates in different gestational age and birth weight groups were as follows: extremely preterm infants 50.0%, very preterm infants 46.6%, moderate preterm infants 32.7%, and late preterm infants 9.8%; birth weight (BW) &lt;1 000 g 60.9%, 1 000 g≤BW&lt;1 500 g 33.9%, and 1 500 g≤BW&lt;2 500 g 10.7%. 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This study selected SGA preterm infants born at less than 37 weeks of gestation and admitted to the Department of Neonatology, Children's Hospital of Soochow Universitywithin 24 hours after birth. The infants were divided into two groups: a cholestasis group and a non-cholestasis group. Clinical data from July 2017 to June 2022 were collected and retrospectively analyzed. Among the 553 SGA preterm infants included, 100 infants (18.1%) developed cholestasis. The incidence rates in different gestational age and birth weight groups were as follows: extremely preterm infants 50.0%, very preterm infants 46.6%, moderate preterm infants 32.7%, and late preterm infants 9.8%; birth weight (BW) &lt;1 000 g 60.9%, 1 000 g≤BW&lt;1 500 g 33.9%, and 1 500 g≤BW&lt;2 500 g 10.7%. Multivariate regression analysis showed that low birth weight, intracranial hemorrhage, duration of invasive ventilation, total amino aci</description><subject>Birth Weight</subject><subject>Cholestasis - epidemiology</subject><subject>Cholestasis - etiology</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Infant, Small for Gestational Age</subject><subject>Male</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><issn>1008-8830</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAYhD2AaCn8BeSRJcGOHdsZUcWXVImlM9Ebxy4uiRP8JgP_niAK00mn506nI4RylmtZVXfHPCDGnDNmMmMEywvJJKvKM7L-91bkEvHIWGlkJS7ISlRSaaXZmrxtuxCDhY56B9OcHFKILU0BP6gHOw0J6eCpfR86hxNgQBoixR66JTEkevhxpzDEpQEOjo7JTS71C-QhTnhFzj106K5PuiH7x4f99jnbvT69bO932VgqlulGWKe48B7K1lglFLDGSu0YB6uF01WhTMEZmEZq3VrXCCNFI8uiAe5bLjbk9rd2TMPnvEyq-4DWdR1EN8xYC17w0lSCqwW9OaFz07u2HlPoIX3Vf5eIbxkpZPI</recordid><startdate>20241015</startdate><enddate>20241015</enddate><creator>Chen, Yu</creator><creator>Zhu, Xue-Ping</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20241015</creationdate><title>Clinical features and risk factors of cholestasis in small for gestational age preterm infants</title><author>Chen, Yu ; Zhu, Xue-Ping</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p560-7b3ce613ffa5d8c636a0bc47e01ac73e79268210a8b477dceb3843b452ba1fd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2024</creationdate><topic>Birth Weight</topic><topic>Cholestasis - epidemiology</topic><topic>Cholestasis - etiology</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Infant, Small for Gestational Age</topic><topic>Male</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>Chen, Yu</creatorcontrib><creatorcontrib>Zhu, Xue-Ping</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhongguo dang dai er ke za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Yu</au><au>Zhu, Xue-Ping</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical features and risk factors of cholestasis in small for gestational age preterm infants</atitle><jtitle>Zhongguo dang dai er ke za zhi</jtitle><addtitle>Zhongguo Dang Dai Er Ke Za Zhi</addtitle><date>2024-10-15</date><risdate>2024</risdate><volume>26</volume><issue>10</issue><spage>1027</spage><pages>1027-</pages><issn>1008-8830</issn><abstract>To investigate the clinical features and risk factors of cholestasis in small for gestational age (SGA) preterm infants. This study selected SGA preterm infants born at less than 37 weeks of gestation and admitted to the Department of Neonatology, Children's Hospital of Soochow Universitywithin 24 hours after birth. The infants were divided into two groups: a cholestasis group and a non-cholestasis group. Clinical data from July 2017 to June 2022 were collected and retrospectively analyzed. Among the 553 SGA preterm infants included, 100 infants (18.1%) developed cholestasis. The incidence rates in different gestational age and birth weight groups were as follows: extremely preterm infants 50.0%, very preterm infants 46.6%, moderate preterm infants 32.7%, and late preterm infants 9.8%; birth weight (BW) &lt;1 000 g 60.9%, 1 000 g≤BW&lt;1 500 g 33.9%, and 1 500 g≤BW&lt;2 500 g 10.7%. 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subjects Birth Weight
Cholestasis - epidemiology
Cholestasis - etiology
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Male
Retrospective Studies
Risk Factors
title Clinical features and risk factors of cholestasis in small for gestational age preterm infants
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