Types, behaviour and therapeutic requirements of inflammatory pouch disorders: Results from the RESERVO study of GETECCU
Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied. This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder be...
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| creator | Mesonero, F. Zabana, Y. Fernández-Clotet, A. Solá, A. Caballol, B. Leo-Carnerero, E. García, M.J. Bertoletti, F. Bastida, G. Suris, G. Casis, B. Ferreiro-Iglesias, R. Calafat, M. Jiménez, I. Miranda-Bautista, J. Lamuela, L.J. Fajardo, I. Torrealba, L. Nájera, R. Sáiz-Chumillas, R.M. González-Partida, I. Vicuña, M. García-Morales, N. Gutiérrez, A. López-García, A. Benítez, J.M. Rubín de Célix, C. Tejido, C. Brunet, E. Hernandez-Camba, A. Suárez, C. Rodríguez-Lago, I. Piqueras, M. Castaño, A. Ramos, L. Sobrino, A. Rodríguez-Grau, M.C. Elosua, A. Montoro, M. Baltar, R. Huguet, J.M. Hermida, B. Caballero-Mateos, A. Sánchez-Guillén, L. Bouhmidi, A. Pajares, R. Baston-Rey, I. López-Sanromán, A. Albillos, A. Barreiro-de Acosta, M. |
| description | Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied.
This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Overall, 338 patients were recruited. The most common disorders were pouchitis (n = 258, 76%), Crohn's disease of the pouch (n = 55, 16%) and cuffitis (n = 25, 7%). Pouchitis presented mainly as chronic (65.2%) and recurrent (87%) forms. Crohn's disease manifested as stricturing/penetrating in 53% of cases and perianal disease in 42%. Patients received multiple therapies: 86% antibiotics, 42% steroids, 27% immunosuppressants, 43% biologics and 27% surgery. Compared with pouchitis, Crohn's disease of the pouch was characterised by a later diagnosis (99 vs. 55 months, p < 0.001) and greater needs for immunosuppressants (OR 3.53, 1.79–6.94, p < 0.0001), biologics (OR 5.45, 2.78–10.6, p < 0.0001) and surgeries (OR 2.65, 1.43–4.89, p < 0.001).
Chronic pouchitis is the most common pouch disorder presentation. These entities have diverse therapeutics requirements, particularly for Crohn's disease of the pouch. |
| doi_str_mv | 10.1016/j.dld.2024.09.023 |
| format | Article |
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This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Overall, 338 patients were recruited. The most common disorders were pouchitis (n = 258, 76%), Crohn's disease of the pouch (n = 55, 16%) and cuffitis (n = 25, 7%). Pouchitis presented mainly as chronic (65.2%) and recurrent (87%) forms. Crohn's disease manifested as stricturing/penetrating in 53% of cases and perianal disease in 42%. Patients received multiple therapies: 86% antibiotics, 42% steroids, 27% immunosuppressants, 43% biologics and 27% surgery. Compared with pouchitis, Crohn's disease of the pouch was characterised by a later diagnosis (99 vs. 55 months, p < 0.001) and greater needs for immunosuppressants (OR 3.53, 1.79–6.94, p < 0.0001), biologics (OR 5.45, 2.78–10.6, p < 0.0001) and surgeries (OR 2.65, 1.43–4.89, p < 0.001).
Chronic pouchitis is the most common pouch disorder presentation. These entities have diverse therapeutics requirements, particularly for Crohn's disease of the pouch.</description><identifier>ISSN: 1590-8658</identifier><identifier>ISSN: 1878-3562</identifier><identifier>EISSN: 1878-3562</identifier><identifier>DOI: 10.1016/j.dld.2024.09.023</identifier><identifier>PMID: 39455313</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adult ; Anti-Bacterial Agents - therapeutic use ; Colitis, Ulcerative - drug therapy ; Colitis, Ulcerative - surgery ; Colitis, Ulcerative - therapy ; Colonic Pouches - adverse effects ; Crohn Disease - drug therapy ; Crohn's disease of the pouch ; Cuffitis ; Female ; Humans ; Immunosuppressive Agents - therapeutic use ; Italy ; Male ; Middle Aged ; Pouchitis ; Pouchitis - drug therapy ; Pouchitis - therapy ; Proctocolectomy, Restorative - adverse effects ; Retrospective Studies</subject><ispartof>Digestive and liver disease, 2025-02, Vol.57 (2), p.566-573</ispartof><rights>2024 Editrice Gastroenterologica Italiana S.r.l.</rights><rights>Copyright © 2024 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1503-df934c6b6ab45faed82abd52a46876173b564995289e1448183213d3a1f36d803</cites><orcidid>0000-0002-1729-6472 ; 0000-0003-0623-9074 ; 0000-0001-6097-7612 ; 0000-0002-7921-6730 ; 0000-0001-7544-451X ; 0000-0001-7676-9842 ; 0000-0002-5460-4139 ; 0000-0002-3874-2638 ; 0000-0001-8898-3141 ; 0000-0002-6517-7005 ; 0000-0002-0469-4332 ; 0000-0003-1133-4578 ; 0000-0002-8120-2485 ; 0000-0001-9539-1689 ; 0000-0001-8661-0608 ; 0000-0001-7513-0764 ; 0000-0003-0130-3778 ; 0000-0002-3425-7758 ; 0000-0002-7864-8187 ; 0000-0003-2335-3792 ; 0000-0002-6006-8328</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1590865824010235$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39455313$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mesonero, F.</creatorcontrib><creatorcontrib>Zabana, Y.</creatorcontrib><creatorcontrib>Fernández-Clotet, A.</creatorcontrib><creatorcontrib>Solá, A.</creatorcontrib><creatorcontrib>Caballol, B.</creatorcontrib><creatorcontrib>Leo-Carnerero, E.</creatorcontrib><creatorcontrib>García, M.J.</creatorcontrib><creatorcontrib>Bertoletti, F.</creatorcontrib><creatorcontrib>Bastida, G.</creatorcontrib><creatorcontrib>Suris, G.</creatorcontrib><creatorcontrib>Casis, B.</creatorcontrib><creatorcontrib>Ferreiro-Iglesias, R.</creatorcontrib><creatorcontrib>Calafat, M.</creatorcontrib><creatorcontrib>Jiménez, I.</creatorcontrib><creatorcontrib>Miranda-Bautista, J.</creatorcontrib><creatorcontrib>Lamuela, L.J.</creatorcontrib><creatorcontrib>Fajardo, I.</creatorcontrib><creatorcontrib>Torrealba, L.</creatorcontrib><creatorcontrib>Nájera, R.</creatorcontrib><creatorcontrib>Sáiz-Chumillas, R.M.</creatorcontrib><creatorcontrib>González-Partida, I.</creatorcontrib><creatorcontrib>Vicuña, M.</creatorcontrib><creatorcontrib>García-Morales, N.</creatorcontrib><creatorcontrib>Gutiérrez, A.</creatorcontrib><creatorcontrib>López-García, A.</creatorcontrib><creatorcontrib>Benítez, J.M.</creatorcontrib><creatorcontrib>Rubín de Célix, C.</creatorcontrib><creatorcontrib>Tejido, C.</creatorcontrib><creatorcontrib>Brunet, E.</creatorcontrib><creatorcontrib>Hernandez-Camba, A.</creatorcontrib><creatorcontrib>Suárez, C.</creatorcontrib><creatorcontrib>Rodríguez-Lago, I.</creatorcontrib><creatorcontrib>Piqueras, M.</creatorcontrib><creatorcontrib>Castaño, A.</creatorcontrib><creatorcontrib>Ramos, L.</creatorcontrib><creatorcontrib>Sobrino, A.</creatorcontrib><creatorcontrib>Rodríguez-Grau, M.C.</creatorcontrib><creatorcontrib>Elosua, A.</creatorcontrib><creatorcontrib>Montoro, M.</creatorcontrib><creatorcontrib>Baltar, R.</creatorcontrib><creatorcontrib>Huguet, J.M.</creatorcontrib><creatorcontrib>Hermida, B.</creatorcontrib><creatorcontrib>Caballero-Mateos, A.</creatorcontrib><creatorcontrib>Sánchez-Guillén, L.</creatorcontrib><creatorcontrib>Bouhmidi, A.</creatorcontrib><creatorcontrib>Pajares, R.</creatorcontrib><creatorcontrib>Baston-Rey, I.</creatorcontrib><creatorcontrib>López-Sanromán, A.</creatorcontrib><creatorcontrib>Albillos, A.</creatorcontrib><creatorcontrib>Barreiro-de Acosta, M.</creatorcontrib><creatorcontrib>On behalf of the GETECCU Young Members Group</creatorcontrib><creatorcontrib>GETECCU Young Members Group</creatorcontrib><title>Types, behaviour and therapeutic requirements of inflammatory pouch disorders: Results from the RESERVO study of GETECCU</title><title>Digestive and liver disease</title><addtitle>Dig Liver Dis</addtitle><description>Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied.
This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Overall, 338 patients were recruited. The most common disorders were pouchitis (n = 258, 76%), Crohn's disease of the pouch (n = 55, 16%) and cuffitis (n = 25, 7%). Pouchitis presented mainly as chronic (65.2%) and recurrent (87%) forms. Crohn's disease manifested as stricturing/penetrating in 53% of cases and perianal disease in 42%. Patients received multiple therapies: 86% antibiotics, 42% steroids, 27% immunosuppressants, 43% biologics and 27% surgery. Compared with pouchitis, Crohn's disease of the pouch was characterised by a later diagnosis (99 vs. 55 months, p < 0.001) and greater needs for immunosuppressants (OR 3.53, 1.79–6.94, p < 0.0001), biologics (OR 5.45, 2.78–10.6, p < 0.0001) and surgeries (OR 2.65, 1.43–4.89, p < 0.001).
Chronic pouchitis is the most common pouch disorder presentation. These entities have diverse therapeutics requirements, particularly for Crohn's disease of the pouch.</description><subject>Adult</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Colitis, Ulcerative - drug therapy</subject><subject>Colitis, Ulcerative - surgery</subject><subject>Colitis, Ulcerative - therapy</subject><subject>Colonic Pouches - adverse effects</subject><subject>Crohn Disease - drug therapy</subject><subject>Crohn's disease of the pouch</subject><subject>Cuffitis</subject><subject>Female</subject><subject>Humans</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Italy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pouchitis</subject><subject>Pouchitis - drug therapy</subject><subject>Pouchitis - therapy</subject><subject>Proctocolectomy, Restorative - adverse effects</subject><subject>Retrospective 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behaviour and therapeutic requirements of inflammatory pouch disorders: Results from the RESERVO study of GETECCU</title><author>Mesonero, F. ; Zabana, Y. ; Fernández-Clotet, A. ; Solá, A. ; Caballol, B. ; Leo-Carnerero, E. ; García, M.J. ; Bertoletti, F. ; Bastida, G. ; Suris, G. ; Casis, B. ; Ferreiro-Iglesias, R. ; Calafat, M. ; Jiménez, I. ; Miranda-Bautista, J. ; Lamuela, L.J. ; Fajardo, I. ; Torrealba, L. ; Nájera, R. ; Sáiz-Chumillas, R.M. ; González-Partida, I. ; Vicuña, M. ; García-Morales, N. ; Gutiérrez, A. ; López-García, A. ; Benítez, J.M. ; Rubín de Célix, C. ; Tejido, C. ; Brunet, E. ; Hernandez-Camba, A. ; Suárez, C. ; Rodríguez-Lago, I. ; Piqueras, M. ; Castaño, A. ; Ramos, L. ; Sobrino, A. ; Rodríguez-Grau, M.C. ; Elosua, A. ; Montoro, M. ; Baltar, R. ; Huguet, J.M. ; Hermida, B. ; Caballero-Mateos, A. ; Sánchez-Guillén, L. ; Bouhmidi, A. ; Pajares, R. ; Baston-Rey, I. ; López-Sanromán, A. ; Albillos, A. ; Barreiro-de Acosta, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1503-df934c6b6ab45faed82abd52a46876173b564995289e1448183213d3a1f36d803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2025</creationdate><topic>Adult</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Colitis, Ulcerative - drug therapy</topic><topic>Colitis, Ulcerative - surgery</topic><topic>Colitis, Ulcerative - therapy</topic><topic>Colonic Pouches - adverse effects</topic><topic>Crohn Disease - drug therapy</topic><topic>Crohn's disease of the pouch</topic><topic>Cuffitis</topic><topic>Female</topic><topic>Humans</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Italy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pouchitis</topic><topic>Pouchitis - drug therapy</topic><topic>Pouchitis - therapy</topic><topic>Proctocolectomy, Restorative - adverse effects</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mesonero, F.</creatorcontrib><creatorcontrib>Zabana, Y.</creatorcontrib><creatorcontrib>Fernández-Clotet, A.</creatorcontrib><creatorcontrib>Solá, A.</creatorcontrib><creatorcontrib>Caballol, B.</creatorcontrib><creatorcontrib>Leo-Carnerero, E.</creatorcontrib><creatorcontrib>García, M.J.</creatorcontrib><creatorcontrib>Bertoletti, F.</creatorcontrib><creatorcontrib>Bastida, G.</creatorcontrib><creatorcontrib>Suris, G.</creatorcontrib><creatorcontrib>Casis, B.</creatorcontrib><creatorcontrib>Ferreiro-Iglesias, R.</creatorcontrib><creatorcontrib>Calafat, M.</creatorcontrib><creatorcontrib>Jiménez, I.</creatorcontrib><creatorcontrib>Miranda-Bautista, J.</creatorcontrib><creatorcontrib>Lamuela, L.J.</creatorcontrib><creatorcontrib>Fajardo, I.</creatorcontrib><creatorcontrib>Torrealba, L.</creatorcontrib><creatorcontrib>Nájera, R.</creatorcontrib><creatorcontrib>Sáiz-Chumillas, R.M.</creatorcontrib><creatorcontrib>González-Partida, I.</creatorcontrib><creatorcontrib>Vicuña, M.</creatorcontrib><creatorcontrib>García-Morales, N.</creatorcontrib><creatorcontrib>Gutiérrez, A.</creatorcontrib><creatorcontrib>López-García, A.</creatorcontrib><creatorcontrib>Benítez, J.M.</creatorcontrib><creatorcontrib>Rubín de Célix, C.</creatorcontrib><creatorcontrib>Tejido, C.</creatorcontrib><creatorcontrib>Brunet, E.</creatorcontrib><creatorcontrib>Hernandez-Camba, A.</creatorcontrib><creatorcontrib>Suárez, C.</creatorcontrib><creatorcontrib>Rodríguez-Lago, I.</creatorcontrib><creatorcontrib>Piqueras, M.</creatorcontrib><creatorcontrib>Castaño, A.</creatorcontrib><creatorcontrib>Ramos, L.</creatorcontrib><creatorcontrib>Sobrino, A.</creatorcontrib><creatorcontrib>Rodríguez-Grau, M.C.</creatorcontrib><creatorcontrib>Elosua, A.</creatorcontrib><creatorcontrib>Montoro, M.</creatorcontrib><creatorcontrib>Baltar, R.</creatorcontrib><creatorcontrib>Huguet, J.M.</creatorcontrib><creatorcontrib>Hermida, B.</creatorcontrib><creatorcontrib>Caballero-Mateos, A.</creatorcontrib><creatorcontrib>Sánchez-Guillén, L.</creatorcontrib><creatorcontrib>Bouhmidi, A.</creatorcontrib><creatorcontrib>Pajares, R.</creatorcontrib><creatorcontrib>Baston-Rey, I.</creatorcontrib><creatorcontrib>López-Sanromán, A.</creatorcontrib><creatorcontrib>Albillos, A.</creatorcontrib><creatorcontrib>Barreiro-de Acosta, M.</creatorcontrib><creatorcontrib>On behalf of the GETECCU Young Members Group</creatorcontrib><creatorcontrib>GETECCU Young Members Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Digestive and liver disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mesonero, F.</au><au>Zabana, Y.</au><au>Fernández-Clotet, A.</au><au>Solá, A.</au><au>Caballol, B.</au><au>Leo-Carnerero, E.</au><au>García, M.J.</au><au>Bertoletti, F.</au><au>Bastida, G.</au><au>Suris, G.</au><au>Casis, B.</au><au>Ferreiro-Iglesias, R.</au><au>Calafat, M.</au><au>Jiménez, I.</au><au>Miranda-Bautista, J.</au><au>Lamuela, L.J.</au><au>Fajardo, I.</au><au>Torrealba, L.</au><au>Nájera, R.</au><au>Sáiz-Chumillas, R.M.</au><au>González-Partida, I.</au><au>Vicuña, M.</au><au>García-Morales, N.</au><au>Gutiérrez, A.</au><au>López-García, A.</au><au>Benítez, J.M.</au><au>Rubín de Célix, C.</au><au>Tejido, C.</au><au>Brunet, E.</au><au>Hernandez-Camba, A.</au><au>Suárez, C.</au><au>Rodríguez-Lago, I.</au><au>Piqueras, M.</au><au>Castaño, A.</au><au>Ramos, L.</au><au>Sobrino, A.</au><au>Rodríguez-Grau, M.C.</au><au>Elosua, A.</au><au>Montoro, M.</au><au>Baltar, R.</au><au>Huguet, J.M.</au><au>Hermida, B.</au><au>Caballero-Mateos, A.</au><au>Sánchez-Guillén, L.</au><au>Bouhmidi, A.</au><au>Pajares, R.</au><au>Baston-Rey, I.</au><au>López-Sanromán, A.</au><au>Albillos, A.</au><au>Barreiro-de Acosta, M.</au><aucorp>On behalf of the GETECCU Young Members Group</aucorp><aucorp>GETECCU Young Members Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Types, behaviour and therapeutic requirements of inflammatory pouch disorders: Results from the RESERVO study of GETECCU</atitle><jtitle>Digestive and liver disease</jtitle><addtitle>Dig Liver Dis</addtitle><date>2025-02</date><risdate>2025</risdate><volume>57</volume><issue>2</issue><spage>566</spage><epage>573</epage><pages>566-573</pages><issn>1590-8658</issn><issn>1878-3562</issn><eissn>1878-3562</eissn><abstract>Inflammatory pouch disorders exhibit a heterogeneous clinical spectrum and therapeutic requirements have not been properly studied.
This retrospective, multicentre study included ulcerative colitis patients with ileal pouch construction and were later diagnosed with an inflammatory pouch disorder between 1995 and 2020. Classifications, behaviour and therapies applied were recorded and compared in the long-term.
Overall, 338 patients were recruited. The most common disorders were pouchitis (n = 258, 76%), Crohn's disease of the pouch (n = 55, 16%) and cuffitis (n = 25, 7%). Pouchitis presented mainly as chronic (65.2%) and recurrent (87%) forms. Crohn's disease manifested as stricturing/penetrating in 53% of cases and perianal disease in 42%. Patients received multiple therapies: 86% antibiotics, 42% steroids, 27% immunosuppressants, 43% biologics and 27% surgery. Compared with pouchitis, Crohn's disease of the pouch was characterised by a later diagnosis (99 vs. 55 months, p < 0.001) and greater needs for immunosuppressants (OR 3.53, 1.79–6.94, p < 0.0001), biologics (OR 5.45, 2.78–10.6, p < 0.0001) and surgeries (OR 2.65, 1.43–4.89, p < 0.001).
Chronic pouchitis is the most common pouch disorder presentation. These entities have diverse therapeutics requirements, particularly for Crohn's disease of the pouch.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>39455313</pmid><doi>10.1016/j.dld.2024.09.023</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-1729-6472</orcidid><orcidid>https://orcid.org/0000-0003-0623-9074</orcidid><orcidid>https://orcid.org/0000-0001-6097-7612</orcidid><orcidid>https://orcid.org/0000-0002-7921-6730</orcidid><orcidid>https://orcid.org/0000-0001-7544-451X</orcidid><orcidid>https://orcid.org/0000-0001-7676-9842</orcidid><orcidid>https://orcid.org/0000-0002-5460-4139</orcidid><orcidid>https://orcid.org/0000-0002-3874-2638</orcidid><orcidid>https://orcid.org/0000-0001-8898-3141</orcidid><orcidid>https://orcid.org/0000-0002-6517-7005</orcidid><orcidid>https://orcid.org/0000-0002-0469-4332</orcidid><orcidid>https://orcid.org/0000-0003-1133-4578</orcidid><orcidid>https://orcid.org/0000-0002-8120-2485</orcidid><orcidid>https://orcid.org/0000-0001-9539-1689</orcidid><orcidid>https://orcid.org/0000-0001-8661-0608</orcidid><orcidid>https://orcid.org/0000-0001-7513-0764</orcidid><orcidid>https://orcid.org/0000-0003-0130-3778</orcidid><orcidid>https://orcid.org/0000-0002-3425-7758</orcidid><orcidid>https://orcid.org/0000-0002-7864-8187</orcidid><orcidid>https://orcid.org/0000-0003-2335-3792</orcidid><orcidid>https://orcid.org/0000-0002-6006-8328</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1590-8658 |
| ispartof | Digestive and liver disease, 2025-02, Vol.57 (2), p.566-573 |
| issn | 1590-8658 1878-3562 1878-3562 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_3121059732 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Anti-Bacterial Agents - therapeutic use Colitis, Ulcerative - drug therapy Colitis, Ulcerative - surgery Colitis, Ulcerative - therapy Colonic Pouches - adverse effects Crohn Disease - drug therapy Crohn's disease of the pouch Cuffitis Female Humans Immunosuppressive Agents - therapeutic use Italy Male Middle Aged Pouchitis Pouchitis - drug therapy Pouchitis - therapy Proctocolectomy, Restorative - adverse effects Retrospective Studies |
| title | Types, behaviour and therapeutic requirements of inflammatory pouch disorders: Results from the RESERVO study of GETECCU |
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