New insights into the function and therapeutic potential of RNA-binding protein TRBP in viral infection, chronic metabolic diseases, brain disorders and cancer

RNA-binding proteins (RBPs) and non-coding RNAs are crucial trans-acting factors that bind to specific cis-acting elements in mRNAs, thereby regulating their stability and translation. The trans-activation response (TAR) RNA-binding protein (TRBP) recognizes precursor microRNAs (pre-miRNAs), modulat...

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Veröffentlicht in:	Life sciences (1973) 2024-12, Vol.358, p.123159, Article 123159
Hauptverfasser:	Ji, Minghui, Li, Lingyu, Yu, Jialing, Wu, Zhao, Sheng, Yuwen, Wang, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Diseases Drug discovery miRNA RISC TRBP
Online-Zugang:	Volltext
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