Comparison of HLA‐haploidentical donors with post‐transplant cyclophosphamide versus HLA‐matched unrelated donors in peripheral blood stem cell transplantation for acute myeloid leukaemia

Summary HLA‐haploidentical haematopoietic cell transplantation with post‐transplant cyclophosphamide (PTCy‐haplo) is emerging as an effective alternative due to donor availability and safety. We conducted a nationwide retrospective study comparing the outcomes of PTCy‐haplo with both anti‐thymocyte...

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Veröffentlicht in:	British journal of haematology 2024-12, Vol.205 (6), p.2376-2386
Hauptverfasser:	Moriguchi, Makoto, Nakamae, Hirohisa, Nishimoto, Mitsutaka, Sugita, Junichi, Yanada, Masamitsu, Toubai, Tomomi, Hasegawa, Yuta, Hino, Masayuki, Nishida, Tetsuya, Kurita, Naoki, Sawa, Masashi, Fukuda, Takahiro, Jinguji, Atsushi, Ota, Shuichi, Matsuoka, Ken‐ichi, Eto, Tetsuya, Hiramoto, Nobuhiro, Ando, Toshihiko, Kawamura, Koji, Kanda, Yoshinobu, Atsuta, Yoshiko, Ohbiki, Marie, Nakasone, Hideki, Konuma, Takaaki
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myeloid leukaemia Acute myeloid leukemia Adolescent Adult Aged Antilymphocyte Serum - therapeutic use Bone marrow transplantation Chronic infection Cyclophosphamide Cyclophosphamide - therapeutic use Female Globulins Graft vs Host Disease - etiology Graft vs Host Disease - prevention & control Graft-versus-host reaction haploidentical donor Hematopoietic stem cells Histocompatibility antigen HLA HLA Antigens - immunology Humans Leukemia Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Male matched unrelated donor Middle Aged Peripheral blood peripheral blood stem cell transplantation Peripheral Blood Stem Cell Transplantation - adverse effects post‐transplant cyclophosphamide Retrospective Studies Stem cell transplantation Transplants & implants Unrelated Donors Young Adult
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