Sphingomyelin Inhibits Hydrolytic Activity of Heterodimeric PLA2 in Model Myelin Membranes: Pharmacological Relevance

In this work, the heterodimeric phospholipase A2, HDP-2, from viper venom was investigated for its hydrolytic activity in model myelin membranes as well as for its effects on intermembrane exchange of phospholipids (studied by phosphorescence quenching) and on phospholipid polymorphism (studied by 1...

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Veröffentlicht in:The Journal of membrane biology 2024-10
Hauptverfasser: Chaudary, Anwaar S., Guo, Yanglin, Utkin, Yuri N., Barancheshmeh, Maryam, Dagda, Ruben K., Gasanoff, Edward S.
Format: Artikel
Sprache:eng
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